The Homer Chamber of Commerce & Visitor Center has represented businesses in the Greater Homer Area since 1948. It is a non-profit organization that supports its members through cooperative economic development and community service. Being a chamber member comes with benefits, including opportunities to connect with local businesses through chamber events advocacy efforts on behalf of the business community and access to information regarding regulatory and political matters that may impact local businesses.

Additionally, the chamber offers resources such as business education workshops, representation at industry trade shows, and networking platforms. One notable program is the Homer Bucks initiative, which generated over $235,000 for circulation in 2021. The chamber also promotes its members' businesses through listings on a travel planning website specific to Homer. It features them in their online business directory as well as in their visitor guide.

Throughout the year, the chamber organizes events, including the fishing tournament on the West Coast and the renowned Kachemak Bay Shorebird Festival. Visitors can find a calendar of events and festivals on their website.