The Columbus Area Chamber of Commerce is a profit organization dedicated to fostering the growth and progress of local businesses, in Columbus, Nebraska. Their main goal is to create a platform where businesses can connect, collaborate and exchange ideas. Additionally they offer benefits to their members including access to business resources, marketing opportunities and educational programs.

Throughout the year the chamber hosts events that play a vital role in showcasing the products and services of local businesses. These events include the Columbus Farmers Market, Columbus Heritage Days and Columbus Christmas Open House. Such gatherings not provide an opportunity for businesses to engage with the community but also cultivate a sense of belongingness among all participants. Furthermore the chamber organizes ribbon cutting ceremonies to celebrate businesses joining the area.