The Chadron Chamber of Commerce is a non-profit organization that supports local businesses in Chadron, Nebraska by fostering growth and development. The chamber plays a role, in facilitating networking opportunities, collaboration, and idea-sharing among businesses. Additionally, it offers advantages to its members, including access to business resources, marketing prospects, and educational programs.

Throughout the year the chamber hosts events within the community. These include the Chadron Farmers Market, Chadron Heritage Days, and the festive Chadron Christmas Open House. These events serve as platforms for businesses to showcase their products and services while establishing connections with the community and nurturing a sense of belonging. Moreover, the chamber also arranges ribbon-cutting ceremonies to celebrate business ventures in the vicinity.