The Auburn Chamber of Commerce in Nebraska is a dynamic organization that unites over 100 businesses, professionals, industrial firms, community members, organizations, and utilities. By joining the Chamber, members contribute to a united effort against challenges facing the business community. The Chamber provides a platform for the exchange of ideas and methods, develops growth and stability programs, supports city officials, area businesses, and the educational system, and sponsors events that showcase the area and its businesses​​.

The Auburn Chamber of Commerce organizes a variety of events throughout the year, creating opportunities for community engagement and business promotion. Notable events include the Auburn Ambassadors Bake-less Bake Sale in February, the "Show Us Your Green" St. Patrick's Day Contest in March, a Bowling Tournament in April, an Easter Coloring Contest, an Annual Golf Tournament in May, and City-Wide Garage Sales in June. The summer months feature an Annual Sidewalk Sale in July and the Nemaha County Fair Booth and Parade in August. In the fall, the Chamber organizes Meals on Wheels in September, a Chamber Banquet in October, and a Christmas Opening and tree Lighting in November. The year ends with a series of festive events in December, including Santa Visits, a Christmas Retail Promotion, a Ugly Sweater Contest, a Tree Decorating Contest, a Residential Lighting Contest, and the Chamber Express Tour of Lights​​.

Overall, the Auburn Chamber of Commerce plays a pivotal role in fostering a vibrant community and supporting the growth of local businesses. Through its events and membership benefits, the Chamber enhances the quality of life in Auburn and contributes significantly to the local economy and community spirit.