The Andrews Chamber of Commerce in North Carolina provides a range of benefits to its members, alongside hosting signature events that contribute significantly to the community's vibrancy and business engagement.

Membership benefits include inclusion in the Chamber's website member directory, with a full page for each member featuring business descriptions, photographs, location, hours of operation, and links to websites and social media. The Chamber also promotes member events on its website calendar and Facebook page. Member promotional materials are displayed at the Chamber office and other strategic locations, ensuring visibility. Members’ materials are included in Welcome to the Mountains Boxes for new residents, and they feature in the Andrews Visitors Guide, which is part of a larger advertising campaign. Chamber members are also listed annually in the "Welcome to Andrews" page of Celebrate Cherokee County Magazine, further enhancing visibility. Special events advertising is prioritized for Chamber members, and the Chamber's referral services give members preferential mention in inquiries about the area. Ribbon cuttings for new businesses are supported by the Chamber, and members get priority booking for booths at Chamber events. Other benefits include sponsorship opportunities for events that strengthen the community's retail, dining, entertainment, and hospitality sectors, and the display of the Chamber decal enhances business credibility​​​​​​​​​​.

In terms of events, the Andrews Chamber of Commerce hosts several signature events throughout the year. "Christmas on Main Street" is a festive event with over 100 craft vendors and musical entertainment, marking the start of the holiday shopping season. The "Spring Fling," held annually, is a street fair and nature expo celebrating Earth Day and the onset of spring. "Food Truck Fridays" offer summer nights of dining and entertainment, and the "Oktoberfest" is a popular fall festival featuring food, beer, and wine, along with local shops and vendors​​​​​​.